If you’re life isn’t overrun with acronyms yet, Dymatize Nutrition hopes you’ll have room for at least one more with their new post-workout supplement called M.P.S.

Set to launch late this summer, M.P.S ostensibly stands for muscle protein synthesis, and is a recovery supplement designed to enhance growth and recovery by activating the much vaunted mTOR pathway, and boosting protein synthesis.

We’ll have a full review for you once M.P.S becomes available. For now, here’s everything you need to know about it.

Protein Synthesis and mTOR

Dymatize Nutrition MPS Reviews
Chances are you’ve come across a supplement at some point that promises to promote activation of something called mTOR. This is a special protein which triggers muscle hypertrophy (growth), by improving protein synthesis.

One of the main ways M.P.S improves mTOR activation is through BCAA’s─ leucine, isoleucine, and valine, as well as leucine metabolites like L-HICA and KIC.

Research shows that supplementing with leucine after exercise helps reverse protein breakdown, and plays an important role in muscle protein synthesis regulation.[1]

Meet The Metabolites

The leucine metabolite l-HICA(L-alpha-hydroxyisocaproic Acid) was studied on soccer players supplementing with 1.5 g of l-HICA a day for 4 weeks. The study concluded that l-HICA not only helped improve protein synthesis, but small increases in muscle mass were also observed.[2]

The other leucine metabolite you’ll find in M.P.S is KIC (L-alpha-ketoisocaproic Acid), which is shown to help reduce muscle damage caused by exercise and preserve skeletal muscle force production when combined with a compound called HMB (beta-hydroxy-beta-methylbutyrate).[3]

Coming Soon

The rumor right now is that M.P.S will be available sometime in August. The formula does have about 2 g of whey protein isolate, but for all intents and purposes it looks like this is essentially a BCAA product with some leucine metabolites thrown in.

I’m all for anything that can improve growth and recovery, so I’m really looking forward to trying M.P.S. Make sure you check back soon for the full review.


[1]Layne E. Norton and Donald K. Layman Leucine Regulates Translation Initiation of Protein Synthesis in Skeletal Muscle after Exercise J. Nutr. February 2006 vol. 136 no. 2 533S-537S
[2] Antti A Mero, corresponding author Tuomo Ojala, Juha J Hulmi, et. al., Effects of alfa-hydroxy-isocaproic acid on body composition, DOMS and performance in athletes J Int Soc Sports Nutr. 2010; 7: 1. Published online Jan 5, 2010
[3] Van Someren, Ken A., Adam J. Edwards, and Glyn Howatson. “Supplementation with [beta]-hydroxy-[beta]-methylbutyrate (HMB) and [alpha]-ketoisocaproic acid (KIC) reduces signs and symptoms of exercise-induced muscle damage in man.” International Journal of Sport Nutrition & Exercise Metabolism 15.4 (2005): 413-424.

About The Author

Brian E. is from southern California and has worked for names like GNC and Vitamin Shoppe as a supplement expert and consultant. He currently lives in Utah and is studying marketing.

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