• Improves protein synthesis with the leucine metabolie HICA
  • Only available in one flavor
7.9Overall Score

Even the most notorious supplement luddite can tell you how essential the amino acid leucine is when it comes to building and repairing new muscle.

Consequently, there’s always going to be a market for leucine laden recovery supplements like the new Syn Matrix 6:5 from Champion Performance.


Syn Matrix Reviews
One of the key ingredients you’re going to find in here is a leucine metabolite called alpha-hydroxyisocaproic acid (HICA). This compound is quickly rising in popularity, and has some very promising research behind it.

In a 4 week study with fifteen healthy male soccer players, research showed that supplementing with 1..5 of l-HICA a day not only helped improve protein synthesis, but resulted in increases in muscle mass as well.[1]

Those Leucine Gains

You’re also going to find 5 g of leucine in here, to help stimulate greater muscle growth and recovery via the mTOR pathway. Triggering this pathway increases protein synthesis, which drives amino acids and nutrients into muscle cells.[1]

What’s more, Syn Matrix features the patented compound BioPerine to help increase nutrient absorption and bioavailability.

Taste, Price, and Availability

I was disappointed to learn that Syn Matrix is only available in one flavor, passion mango. The flavor is one the sweet side though, and I thought it was pretty good.

It would be nice to see this in a flavorless version, however, so it could be added to a post-workout shake or something else that’s similar. Right now a 30 serving container is available at most online retailers for around $34.99-$42.99.

Is Syn Matrix Effective?

I did feel like Syn Matrix 6:5 helped a little bit with recovery, but it is difficult to get excited about a glorified leucine supplement. With only 6 g of why protein isolate, you’re still going to need to stack Syn Matrix with additional carbs and protein for a full post-workout recovery.

That being said, this is a good way to get extra leucine, the king of amino acids when it comes to muscle growth. If your amino acid supplement is underdosed or you’re looking to get some extra leucine, Syn Matrix 6.5 isn’t a bad way to go.

[1] Antti A Mero, corresponding author Tuomo Ojala, Juha J Hulmi, et. al., Effects of alfa-hydroxy-isocaproic acid on body composition, DOMS and performance in athletes J Int Soc Sports Nutr. 2010; 7: 1. Published online Jan 5, 2010
[2] Layne E. Norton and Donald K. Layman Leucine Regulates Translation Initiation of Protein Synthesis in Skeletal Muscle after Exercise J. Nutr. February 2006 vol. 136 no. 2 533S-537S

About The Author

Brian E. is from southern California and has worked for names like GNC and Vitamin Shoppe as a supplement expert and consultant. He currently lives in Utah and is studying marketing.

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